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HIV/AIDS Medicines

HIV/AIDS Medicines

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• Journal Articles

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Summary

In the early 1980s, when the HIV/AIDS epidemic began, patients rarely lived longer than a few years. But today, there are many effective medicines to fight the infection, and people with HIV have longer, healthier lives.
There are five major types of medicines:

• Reverse transcriptase (RT) inhibitors - interfere with a critical step during the HIV life cycle and keep the virus from making copies of itself
• Protease inhibitors - interfere with a protein that HIV uses to make infectious viral particles
• Fusion inhibitors - block the virus from entering the body's cells
• Integrase inhibitors - block an enzyme HIV needs to make copies of itself
• Multidrug combinations - combine two or more different types of drugs into one

These medicines help people with HIV, but they are not perfect. They do not cure HIV/AIDS. People with HIV infection still have the virus in their bodies. They can still spread HIV to others through unprotected sex and needle sharing, even when they are taking their medicines.

NIH: National Institute of Allergy and Infectious Diseases

Start Here

• AIDSinfo Drug Database (AIDSinfo) Available in Spanish
• FDA-Approved HIV Medicines (AIDSinfo) Available in Spanish
• HIV and AIDS: Medicines to Help You (Food and Drug Administration)
• HIV Treatment: The Basics (AIDSinfo)
• Taking Current Antiretroviral Drugs (New Mexico AIDS Education and Training Center) Available in Spanish
• Treatment for HIV (Department of Veterans Affairs)
• Treatment of HIV Infection (National Institute of Allergy and Infectious Diseases)
• Types of HIV/AIDS Antiretroviral Drugs (National Institute of Allergy and Infectious Diseases)

Latest News

• HIV Therapy May Also Lower Risk for Hepatitis B, Study Says (10/12/2015, HealthDay)
• Almost Half of American Adults with HIV Don't Take Meds (09/24/2015, HealthDay)
• More Evidence Daily Pill Can Prevent HIV Transmission (09/10/2015, HealthDay)
• Early Antiretroviral Therapy Prevents Non-AIDS Outcomes in HIV-Infected People (07/20/2015, National Institute of Allergy and Infectious Diseases)
• More News on HIV/AIDS Medicines

Related Issues

• Are You Taking Medication as Prescribed? (Food and Drug Administration)
• Blood Sugar and Fats (New Mexico AIDS Education and Training Center) Available in Spanish
• Body Composition Tests (New Mexico AIDS Education and Training Center) Available in Spanish
• Body Shape Changes (Lipodystrophy) (New Mexico AIDS Education and Training Center) Available in Spanish
• CDC Vital Signs: HIV Care Saves Lives Available in Spanish
• CDC Vital Signs: New Hope for Stopping HIV (Centers for Disease Control and Prevention)
• Drug Dosing Toolkit (Department of Veterans Affairs)
• Drug Interactions (New Mexico AIDS Education and Training Center) Available in Spanish
• Drug Resistance (AIDSinfo) Available in Spanish
• Following an HIV Regimen: Steps to Take Before and After Starting HIV Medicines (AIDSinfo) Available in Spanish
• HIV Medication Adherence (AIDSinfo)
• HIV Medicines and Side Effects (AIDSinfo)
• HIV Resistance Testing (New Mexico AIDS Education and Training Center) Available in Spanish
• HIV Treatment Adherence (AIDS.gov)
• Mitochondrial Toxicity (New Mexico AIDS Education and Training Center) Available in Spanish
• PEP (Post-Exposure Prophylaxis) 101 (Centers for Disease Control and Prevention) Available in Spanish
• Peripheral Neuropathy (New Mexico AIDS Education and Training Center) Available in Spanish
• Post-Exposure Prophylaxis (AIDS.gov)
• Pre-Exposure Prophylaxis (PrEP) (AIDS.gov)
• PrEP (Pre-Exposure Prophylaxis) 101 (Centers for Disease Control and Prevention) Available in Spanish
• Recreational Drugs and HIV (New Mexico AIDS Education and Training Center) Available in Spanish
• Side Effects (New Mexico AIDS Education and Training Center) Available in Spanish
• Side Effects of HIV Medicines: HIV and Diabetes (AIDSinfo)
• Side Effects of HIV Medicines: HIV and Hepatotoxicity (AIDSinfo)
• Side Effects of HIV Medicines: HIV and Hyperlipidemia (AIDSinfo)
• Side Effects of HIV Medicines: HIV and Lactic Acidosis (AIDSinfo)
• Side Effects of HIV Medicines: HIV and Lipodystrophy (AIDSinfo)
• Side Effects of HIV Medicines: HIV and Osteoporosis (AIDSinfo)
• Side Effects of HIV Medicines: HIV and Rash (AIDSinfo)
• What to Start: Selecting a First HIV Regimen (AIDSinfo) Available in Spanish
• When to Start Antiretroviral Therapy (AIDSinfo)

Specific Conditions

• Antiretroviral Drugs Used in the Treatment of HIV Infection (Food and Drug Administration)
• Approved Generic Formulations of Antiretroviral Drugs Used in the Treatment of HIV Infection (Food and Drug Administration)

Images

• Drugs That Fight HIV-1 (AIDSinfo) - PDF

Videos

• HIV Medications and Risk for Cardiovascular Disease (American Heart Association)

Statistics and Research

• Efavirenz and the Risk for Suicidal Behaviors (American College of Physicians) - PDF

Clinical Trials

• ClinicalTrials.gov: Anti-HIV Agents (National Institutes of Health)
• ClinicalTrials.gov: Anti-HIV Agents (National Institutes of Health)
• ClinicalTrials.gov: Antiretroviral Therapy, Highly Active (National Institutes of Health)
• ClinicalTrials.gov: HIV Infections (National Institutes of Health)
• ClinicalTrials.gov: Pre-Exposure Prophylaxis (National Institutes of Health)

Journal ArticlesReferences and abstracts from MEDLINE/PubMed (National Library of Medicine)

• Article: CLINICAL PRACTICE. Primary Care for Men Who Have Sex with...
• Article: Cost Analysis of Adult Male Circumcision with the PrePex Device...
• Article: The Vancouver Consensus: antiretroviral medicines, medical evidence, and political will.
• HIV/AIDS Medicines -- see more articles

Reference Desk

• AIDSinfo Glossary (AIDSinfo) Available in Spanish

Find an Expert

• AIDS.gov
• AIDSinfo (Department of Health and Human Services) Available in Spanish
• NIAID Division of Acquired Immunodeficiency Syndrome (National Institute of Allergy and Infectious Diseases)

Finance and Policy

• AIDS Drug Assistance Programs (ADAPs) (Henry J. Kaiser Family Foundation)

Children

• Approved Antiretroviral Drugs Used for Pediatric Treatment of HIV Infection (Food and Drug Administration)

Patient Handouts

• FDA-Approved HIV Medicines (AIDSinfo) Available in Spanish

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Related Health Topics

• HIV/AIDS

National Institutes of Health

The primary NIH organization for research on HIV/AIDS Medicines is the National Institute of Allergy and Infectious Diseases

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Page last updated on 13 October 2015 Topic last reviewed: 22 September 2014