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Tuesday, November 24, 2015

VIRUS / ALERGIAS / RESPIRATORIO / PEDIATRIA / ASMA



Virus respiratorio sincitial

Otros nombres: Virus sincitial respiratorio 
     

Introducción

El virus respiratorio sincitial causa síntomas leves, similares a los de un resfrío, en adultos y niños mayores. Puede causar problemas serios en bebés, incluyendo neumonía y problemas respiratorios severos. Los bebés prematuros y los que tienen otros problemas de salud corren el mayor riesgo. Un menor de edad con el virus puede presentar fiebre, obstrucción nasal, tos y dificultades para respirar. Análisis de laboratorio pueden confirmar si su hijo lo tiene. No hay tratamientos específicos. Usted debe dar a su hijo líquidos para prevenir la deshidratación. De ser necesario, también puede darle analgésicos (aunque no aspirina) para la fiebre y el dolor de cabeza.
El virus respiratorio sincitial se transmite fácilmente de una persona a otra. Puede adquirirse por contacto directo con alguien que lo tiene o por tocar objetos infectados, como juguetes o superficies como mostradores. El lavado frecuente de manos y no compartir utensilios para comer o beber son formas simples de prevenir que se propague el virus. En la actualidad, no existe una vacuna contra el virus respiratorio sincitial.
Centros para el Control y la Prevención de Enfermedades

Comience aquí

Diagnósticos/Síntomas

Condiciones específicas


Monday, November 23, 2015

WHEAT GENOME PUZZLE / SECOND STAPLE IN FOOD ALLERGY, WORLDWIDE

Wheat Allergy as treated by Carlos E Mijares MD, former fellow in Allergy / Immunology, pediatrics  at University of Kansas, USA.
Currently, practicing at www.centromedicodecaracas.com,ve
carlosmixares@gmail.com

Elimination Diet Sheet : Wheat, Oats, Rice, Barley, Rye. All breads and baked goods, flour, cake,crackers, doughnuts, cookies, waffles, pancakes, pretzels, icecream cones, pie crust, macaroons, rolls, buns, cereals, macaroni, spaghetti, noodles, gravy.

Common Food Relationships:
Family or Class     Important Members      Usual Manifestations                Cross reactivity

Buckwheat            Buckwheat, rhubarb      Rare offenders;                          Probably strong
                                                                    buckwheat useful
                                                                    in wheat-sensitive
                                                                    children




Insights and opinion from BioMed Central on the latest biology research and developments in the field. About this blog »



Durum roll please: updated genome a huge milestone for designing high-yield sustainable wheat

The updated wheat genome sequence, released today, is a new step toward generating improved wheat varieties. Here, Genome Biology's Dominique Morneau outlines the challenges and opportunities that accompany the sequencing of the wheat genome.
Bread wheat (Triticum aestivum) is the second most highly produced cereal worldwide, grown on more than 215 million hectares, and the leading source of vegetable protein in human food. It was first domesticated in western Asia around 11,700 years ago, after which it spread to North Africa, Europe, and East Asia. Scientists are currently trying to figure out how to feed a growing population; in the next 50 years, we will need to grow more wheat than has been produced since the dawn of agriculture.
The key to improving wheat lies in identifying genes that can be exploited to meet the increased demand for high quality food. Unfortunately, sequencing the wheat genome is proving to be quite difficult.

The complexity of the wheat genome

Bread wheat is an allohexaploid, meaning that it has six sets of seven chromosomes derived from three different progenitor species (Triticum uratru, Aegilops speltoides, and Aegilops tauschii). The wheat genome is divided into three subgenomes: A, B, and D, each of which is almost twice as large as the human genome.
The wheat genome itself isn’t any harder to sequence than smaller genomes. What researchers have been struggling with is putting all the letters together in the right order. The wheat genome contains 17 gigabases (compared to the 3 gigabase human genome), and 80% of it is repetitive sequences. Using whole-genome shotgun sequencing methods thus becomes unattractive, since they generate reads of 500-1000 bases.
To understand why this problem is so complex, imagine a jigsaw puzzle with 17 million small pieces, 80% of which are very similar to each other. An international consortium of 1,100 researchers from 55 countries has been working on sequencing and assembling the wheat genome for the last 10 years!

The wheat genome – spelt out here

The wheat genome is currently being sequenced chromosome by chromosome. In July 2014, a draft of the full genome was published in the journal Science along with a reference sequence for chromosome 3B. Because of the complexity of the genome, the draft genome has lower accuracy, with segments either missing or in the wrong order or orientation.
Since then, work has focused on producing reference-quality assemblies for the remaining chromosomes – filling in the gaps with high accuracy and removing ambiguity in the order of segments – and mapping specific genes and genomic features. Other researchers have used the draft genome to study the evolution of wheat and other cereals, and to find variability in loci encoding agronomically important traits.
Today, The Genome Analysis Centre (TGAC) in Norwich, UK, has made a more complete and accurate wheat genome assembly available to the research community. The updated genome is now assembled into fewer, larger sections of DNA covering regions that were previously not sequenced. These regions include many of the large and complex groups of genes in wheat that contribute to the nutritional and bread-making quality of the grain.
wheat 2
Photo: The Genome Analysis Centre

Flour power

Here at Genome Biology, we’re big fans of wheat genomics, and have put together a collection of articles that we’ve published in the last year. Highlights include a more in-depth understanding of the structure, evolution, and expression of genes from chromosome 3B, a new method for assembling the wheat genome, finding sequence variations across the genome, and identifying genes that produce important traits that we may want to exploit, like grain dormancy.
But there’s more to wheat genomics than meets the eye. Growing wheat also means dealing with a slew of pathogens that affect yield. As interest in wheat genomics grows, so too does work in pathogenomics to prevent productivity losses, like those caused by the wheat yellow rust pathogen (Puccinia striiformis f. sp. tritici).

Never miss a triticum

The updated wheat genome is another step toward a chromosome-based complete genome in this important crop species. With this information, plant breeders will have high quality tools at their disposal to identify specific genes affecting agronomically important traits, such as yield, grain size and weight, nutritional quality, and stress tolerance. This will enable farmers and breeders to produce new wheat varieties better adapted to increasing demand in a changing climate.


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